FET::CREB fusion in a lung nodule

The list of tumours with fusions involving the FET (EWSR1, FUS) and CREB (CREB1, ATF1, or CREM) families of genes is ever-expanding. These are promiscuous genes that drive neoplasia in a wide variety of anatomical sites, often without being recognized as such – but that doesn’t mean tumours with these molecular lesions are always primary… Continue reading FET::CREB fusion in a lung nodule

NGS in a Québec NSCLC cohort

I collaborated on this study that Mark Sorin and colleagues published in Cancer Treatment and Research Communications, detailing the molecular profile of a large (n=997) cohort of patients at the McGill University Health Centre, the institution where I am undergoing residency training. Québec is a province with unique outcomes and environmental exposures related to lung… Continue reading NGS in a Québec NSCLC cohort