Although Thoracic SMARCA4-deficient undifferentiated tumour (SD-UT) is a recognized entity in the 5th edition of the WHO classification of thoracic tumors, this alteration occurs in garden-variety lung cancer as well (and in many other tumors too!) In fact, it is likely SD-UT exists on a continuum with SMARCA4-deficient lung cancer. I recently came across an… Continue reading SMARCA4-deficiency: a continuum